Nature Nanotechnology, Published online: 06 August 2025; doi:10.1038/s41565-025-01989-y
The glycocalyx, the cell’s sugar coat, has key roles in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible until now. Here, we combine metabolic labelling with ångström-resolution fluorescence microscopy to visualize individual sugars within glycans on the cell surface, thus obtaining molecular-resolution images of the glycocalyx.
Source link
