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Home»Nanotechnology»Bioengineered photosynthetic nanothylakoids reshape the inflammatory m…
Nanotechnology

Bioengineered photosynthetic nanothylakoids reshape the inflammatory m…

Editor-In-ChiefBy Editor-In-ChiefDecember 5, 2025No Comments9 Mins Read
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  • Aletaha, D. & Smolen, J. S. Diagnosis and management of rheumatoid arthritis: a review. JAMA 320, 1360–1372 (2018).

    Article 
    PubMed 

    Google Scholar
     

  • Gravallese, E. M. & Firestein, G. S. Rheumatoid arthritis—common origins, divergent mechanisms. N. Engl. J. Med. 388, 529–542 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zhang, F. et al. Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. Nature 623, 616–624 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Fearon, U., Hanlon, M. M., Floudas, A. & Veale, D. J. Cellular metabolic adaptations in rheumatoid arthritis and their therapeutic implications. Nat. Rev. Rheumatol. 18, 398–414 (2022).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Buckley, C. D., Ospelt, C., Gay, S. & Midwood, K. S. Location, location, location: how the tissue microenvironment affects inflammation in RA. Nat. Rev. Rheumatol. 17, 195–212 (2021).

    Article 
    PubMed 

    Google Scholar
     

  • Weyand, C. M. & Goronzy, J. J. Immunometabolism in early and late stages of rheumatoid arthritis. Nat. Rev. Rheumatol. 13, 291–301 (2017).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Boutet, M. A. et al. Novel insights into macrophage diversity in rheumatoid arthritis synovium. Autoimmun. Rev. 20, 102758 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Martel-Pelletier, J. et al. Osteoarthritis. Nat. Rev. Dis. Prim. 2, 16072 (2016).

    Article 
    PubMed 

    Google Scholar
     

  • Burmester, G. R. & Pope, J. E. Novel treatment strategies in rheumatoid arthritis. Lancet 389, 2338–2348 (2017).

    Article 
    PubMed 

    Google Scholar
     

  • Nissen, S. E. et al. Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis. N. Engl. J. Med. 375, 2519–2529 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Erhardt, D. P. et al. Low persistence rates in patients with rheumatoid arthritis treated with triple therapy and adverse drug events associated with sulfasalazine. Arthritis Care Res. 71, 1326–1335 (2019).

    Article 
    CAS 

    Google Scholar
     

  • Zhu, Y. et al. Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials. Nano Today 42, 101358 (2022).

    Article 
    CAS 

    Google Scholar
     

  • Nizet, V. & Johnson, R. S. Interdependence of hypoxic and innate immune responses. Nat. Rev. Immunol. 9, 609–617 (2009).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhao, Y. et al. Nanozyme-reinforced hydrogel as a H2O2-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy. Nat. Commun. 13, 6758 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhang, Q. et al. Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis. Nat. Nanotechnol. 13, 1182–1190 (2018).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Jia, M. et al. Messenger nanozyme for reprogramming the microenvironment of rheumatoid arthritis. ACS Appl. Mater. Interfaces 15, 338–353 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kim, J. et al. Synergistic oxygen generation and reactive oxygen species scavenging by manganese ferrite/ceria co-decorated nanoparticles for rheumatoid arthritis treatment. ACS Nano 13, 3206–3217 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Yang, Y. et al. Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and re-polarization. Biomaterials 264, 120390 (2021).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Yang, J., Yang, B. & Shi, J. A nanomedicine-enabled ion-exchange strategy for enhancing curcumin-based rheumatoid arthritis therapy. Angew. Chem. Int. Ed. 62, e202310061 (2023).

    Article 
    CAS 

    Google Scholar
     

  • Xu, C. et al. Arthritic microenvironment actuated nanomotors for active rheumatoid arthritis therapy. Adv. Sci. 10, e2204881 (2023).

    Article 

    Google Scholar
     

  • Chen, J. et al. Photoacoustic image-guided biomimetic nanoparticles targeting rheumatoid arthritis. Proc. Natl Acad. Sci. USA 119, e2213373119 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Koo, S. et al. Ceria-vesicle nanohybrid therapeutic for modulation of innate and adaptive immunity in a collagen-induced arthritis model. Nat. Nanotechnol. 18, 1502–1514 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Del Giudice, G. et al. An ancestral molecular response to nanomaterial particulates. Nat. Nanotechnol. 18, 957–966 (2023).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Stater, E. P., Sonay, A. Y., Hart, C. & Grimm, J. The ancillary effects of nanoparticles and their implications for nanomedicine. Nat. Nanotechnol. 16, 1180–1194 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gao, J. et al. Intracerebral fate of organic and inorganic nanoparticles is dependent on microglial extracellular vesicle function. Nat. Nanotechnol. 19, 376–386 (2024).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Li, Y. et al. Innate immunity-modulating nanobiomaterials for controlling inflammation resolution. Matter 7, 3811–3844 (2024).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhang, M. et al. Edible ginger-derived nanoparticles: a novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer. Biomaterials 101, 321–340 (2016).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Chen, Q. et al. Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation. Acta Pharm. Sin. B 12, 907–923 (2022).

    Article 
    PubMed 

    Google Scholar
     

  • Feng, T., Ahmed, W., Ahmed, T. & Chen, L. Nanoparticles derived from herbal preparations may represent a novel nucleic acid therapy. Interdiscip. Med. 2, e20230029 (2024).

    Article 
    CAS 

    Google Scholar
     

  • Miller, T. E. et al. Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts. Science 368, 649–654 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Gao, F. et al. Artificial photosynthetic cells with biotic–abiotic hybrid energy modules for customized CO2 conversion. Nat. Commun. 14, 6783 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hou, L. et al. Hybrid-membrane-decorated Prussian blue for effective cancer immunotherapy via tumor-associated macrophages polarization and hypoxia relief. Adv. Mater. 34, e2200389 (2022).

    Article 
    PubMed 

    Google Scholar
     

  • Suk, J. S., Xu, Q., Kim, N., Hanes, J. & Ensign, L. M. PEGylation as a strategy for improving nanoparticle-based drug and gene delivery. Adv. Drug Deliv. Rev. 99, 28–51 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kobayashi, K., Jimbo, H., Nakamura, Y. & Wada, H. Biosynthesis of phosphatidylglycerol in photosynthetic organisms. Prog. Lipid Res. 93, 101266 (2024).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Pali, T., Garab, G., Horvath, L. I. & Kota, Z. Functional significance of the lipid-protein interface in photosynthetic membranes. Cell. Mol. Life Sci. 60, 1591–1606 (2003).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Liu, J. et al. Delivery of biomimetic liposomes via meningeal lymphatic vessels route for targeted therapy of Parkinson’s disease. Research 6, 0030 (2023).

  • Hao, M. et al. Combination of metabolic intervention and T cell therapy enhances solid tumor immunotherapy. Sci. Transl. Med. 12, eaaz6667 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Barber, J. A mechanism for water splitting and oxygen production in photosynthesis. Nat. Plants 3, 17041 (2017).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kafri, M. et al. Systematic identification and characterization of genes in the regulation and biogenesis of photosynthetic machinery. Cell 186, 5638–5655.25 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hald Albertsen, C. et al. The role of lipid components in lipid nanoparticles for vaccines and gene therapy. Adv. Drug Deliv. Rev. 188, 114416 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Chen, P. et al. A plant-derived natural photosynthetic system for improving cell anabolism. Nature 612, 546–554 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Alivernini, S. et al. Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. Nat. Med. 26, 1295–1306 (2020).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Smolen, J. S. et al. Rheumatoid arthritis. Nat. Rev. Dis. Prim. 4, 18001 (2018).

    Article 
    PubMed 

    Google Scholar
     

  • Lan, R. et al. Folate receptor-targeted NIR-II dual-model nanoprobes for multiscale visualization of macrophages in rheumatoid arthritis. Adv. Func. Mat. 33, 2300342 (2023).

    Article 
    CAS 

    Google Scholar
     

  • Ma, Y. et al. DNA origami as a nanomedicine for targeted rheumatoid arthritis therapy through reactive oxygen species and nitric oxide scavenging. ACS Nano 16, 12520–12531 (2022).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Hegarty, L. M., Jones, G. R. & Bain, C. C. Macrophages in intestinal homeostasis and inflammatory bowel disease. Nat. Rev. Gastroenterol. Hepatol. 20, 538–553 (2023).

    Article 
    PubMed 

    Google Scholar
     

  • Venkatesan, R. et al. Immuno-modulating theranostic gold nanocages for the treatment of rheumatoid arthritis in vivo. Chem. Eng. J. 446, 136868 (2022).

    Article 
    CAS 

    Google Scholar
     

  • Tardito, S. et al. Macrophage M1/M2 polarization and rheumatoid arthritis: a systematic review. Autoimmun. Rev. 18, 102397 (2019).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Liu, Y. et al. Multifunctional Janus nanoplatform for efficiently synergistic theranostics of rheumatoid arthritis. ACS Nano 17, 8167–8182 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • You, D. G. et al. Metabolically engineered stem cell–derived exosomes to regulate macrophage heterogeneity in rheumatoid arthritis. Sci. Adv. 7, eabe0083 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Rodriguez-Ramiro, I. et al. Pharmacological and genetic increases in liver NADPH levels ameliorate NASH progression in female mice. Free Radic. Biol. Med. 210, 448–461 (2024).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Weng, L. et al. Surplus fatty acid synthesis increases oxidative stress in adipocytes and lnduces lipodystrophy. Nat. Commun. 15, 133 (2024).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Fearon, U., Canavan, M., Biniecka, M. & Veale, D. J. Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis. Nat. Rev. Rheumatol. 12, 385–397 (2016).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Jia, N. et al. Metabolic reprogramming of proinflammatory macrophages by target delivered roburic acid effectively ameliorates rheumatoid arthritis symptoms. Signal Transduct. Target Ther. 8, 280 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Guan, F. et al. Tissue macrophages: origin, heterogenity, biological functions, diseases and therapeutic targets. Signal Transduct. Target Ther. 10, 93 (2025).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wang, Z. et al. A targeted exosome therapeutic confers both CfDNA scavenging and macrophage polarization for ameliorating rheumatoid arthritis. Adv. Mater. 35, e2302503 (2023).

    Article 
    PubMed 

    Google Scholar
     

  • Li, L. et al. M2 macrophage-derived sEV regulate pro-inflammatory CCR2+ macrophage subpopulations to favor post-AMI cardiac repair. Adv. Sci. 10, e2202964 (2023).

    Article 

    Google Scholar
     

  • Qiao, Y. et al. Engineered algae: a novel oxygen-generating system for effective treatment of hypoxic cancer. Sci. Adv. 6, eaba5996 (2020).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wang, W. et al. Engineering micro oxygen factories to slow tumour progression via hyperoxic microenvironments. Nat. Commun. 13, 4495 (2022).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhong, D. et al. Microalgae-based hydrogel for inflammatory bowel disease and its associated anxiety and depression. Adv. Mater. 36, e2312275 (2024).

    Article 
    PubMed 

    Google Scholar
     

  • Ouyang, J. et al. Biomimetic nanothylakoids for efficient imaging-guided photodynamic therapy for cancer. Chem. Commun. 54, 3468–3471 (2018).

    Article 
    CAS 

    Google Scholar
     

  • Chen, B., Ni, Y., Liu, J., Zhang, Y. & Yan, F. Bone marrow-derived mesenchymal stem cells exert diverse effects on different macrophage subsets. Stem Cells Int. 2018, 8348121 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Wynn, T. A., Chawla, A. & Pollard, J. W. Macrophage biology in development, homeostasis and disease. Nature 496, 445–455 (2013).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Ma, C. et al. Significantly improving the bioefficacy for rheumatoid arthritis with supramolecular nanoformulations. Adv. Mater. 33, e2100098 (2021).

    Article 
    PubMed 

    Google Scholar
     



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